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7% of subjects treated with Cerumenex, Murine, and placebo, respectively, experienced resolution of cerumen occlusion and/or impaction. Occlusion level was reassessed after each application of medication or placebo and after each irrigation procedure. Return To Duty Physical. State and age restrictions may apply. Because full visualization of the tympanic membrane is the ultimate goal of many cerumen removal procedures, the scale was based on the assessor's ability to visualize the tympanic membrane, rather than on the amount of cerumen present or removed. Ear wax removal san diego county. We serve patients from El Cajon CA, Wells Park CA, Rancho San Diego CA, Hillsdale CA, Alpine CA, Santee CA, and Jamul CA. 2004;130(10):1175–1177. It is generally accepted that cerumen removal is a commonly performed, time-consuming procedure that carries added risk if mechanical means or lengthy irrigation procedures are required. We recommend updating your browser or using a different one like Chrome, Firefox, or Safari.
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Randomized, subject- and observer-blind, placebo-controlled, clinical trial. For more information, call us or book a visit online. By the end of treatment, 29. 5%) required 2 applications, whereas 9. We can treat you for all of your colds, allergies, annual physicals, and even treat you for diabetes, hypertension, hypothyroidism. Results after a single application showed that no 1 test article appeared more effective than the others in removing occlusions. 4 Items used to aid earwax removal include household agents such as water and olive oil, stool softeners, and chemicals such as hydrogen peroxide, carbamide peroxide, and surfactants. Randomized, Placebo-Controlled Evaluation of Cerumenex and Murine Earwax Removal Products | Otolaryngology | JAMA Otolaryngology–Head & Neck Surgery | JAMA Network. These values were not statistically significantly different from one another. East County Urgent Care serves the east San Diego county and Cajon Valley area with walk-in treatment of most family medicine needs.
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DOT DMV Driver Physicals. Bug Bites and Insect Stings. Cold Sores, Canker and Mouth Sores. Baseline occlusion levels were mild (n = 10), moderate (n = 26), or complete (n = 38). Urinary Tract and Bladder Infections. Walgreens Pharmacy administers applicable vaccinations for children ages three and older. Results demonstrated that neither Cerumenex nor Murine was superior to placebo in resolving the occlusion due to cerumen. Family Practice Clinic – East County Urgent Care. However, these products may also be irritating and/or ineffective. If the ear canal was cleared of cerumen after a single application and irrigation, the second application was not conducted. 64% sodium chloride and physiologic concentrations of multiple electrolytes; Alcon Laboratories Inc, Fort Worth, Tex). Ear wax removal bay area. Poison Ivy, Poison Oak. While in many instances earwax can be removed mechanically, specialized instruments such as operating microscopes, suction, and/or flushing equipment may not be available in a primary care setting. Vaccines are subject to availability; certain vaccines may not be available in all stores.
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Upper Respiratory Infections. The currently marketed ceruminolytic products, Cerumenex and Murine, are no more effective than a saline placebo in removing earwax. Providing quality medical care without the wait when: - Your primary care physician's office is closed. 2, 3 Ceruminolytic agents that soften and/or loosen earwax from the tympanic membrane can facilitate the removal process. Please consider updating your browser. To maintain masking of the clinical assessor and subject, test articles were stored out of view and were administered by clinic staff who did not perform clinical assessments. Correspondence: Peter S. Roland, MD, Department of Otolaryngology–Head and Neck Surgery, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75235-9035 (). Bronchitis and Coughs. Undesirable complications were minimal with all 3 test articles.
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On site EKG machine. Because this was planned as a descriptive study, no power calculations were made prior to study initiation. 5% had successful treatment outcomes after only 1 application and rinse. To evaluate the efficacy of 2 ceruminolytic products, Cerumenex Eardrops (Purdue Frederick Company, Norwalk, Conn) and Murine Ear Drops (Abbott Laboratories, Abbott Park, Ill), in subjects with partial or complete occlusion of the ear canal due to cerumen. While placebo appeared to be more effective than both ceruminolytics, the difference between Cerumenex and placebo was not statistically significant (P =. As required by editorial policy, an independent statistician, William Frawley, PhD, Department of Statistics, University of Texas Southwestern Medical Center, Dallas, reviewed the data, and his analysis confirmed the statistical evaluation. Each application was followed by a standardized irrigation procedure using a WaterPik Oral Jet Irrigator (WaterPik Technologies, Inc, Fort Collins, Colo), modified with a Grossan tip (Hydro Med, Inc, Sherman Oaks, Calif). Limiting the duration of treatment and controlling the irrigation procedure ensured consistent application of treatments and allowed for reliable comparisons between products.
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The change from baseline degree of occlusion to a resolved, improved, or unchanged/worsened condition is depicted in Figure 1. Our Family Care and Medical Care Services will provide you with complete Medical Care, for your Health and Well being. Volunteers were enrolled over a 2-month period (July-September 2001) at a single corporate site (sponsor's research clinic). There were 51 men and 23 women (male-female ratio, 2. Of 24 occlusions treated with Cerumenex, 2 (8%) cleared after 1 treatment; of 26 occlusions treated with Murine, 3 (12%) cleared after 1 treatment; and of 24 occlusions treated with placebo, 2 (8%) cleared after 1 treatment. Important: You're using Internet Explorer 8, which is unsupported. Sprains, Strains, Joint Pain. Subjects were asked to lie on their side with the study ear facing upward during treatment. 10 Further assessment of the ceruminolytic properties of saline might potentially be done using comparators such as pure water or no pretreatment in a controlled clinical setting. These events are presented in Table 3. We can see you for your cough and cold when your primary physician is not available. The study design also replicated actual use of a ceruminolytic product in an outpatient clinic setting. MMR (Measles, Mumps, Rubella).
Neither Cerumenex nor Murine was superior to saline placebo. Accepted for publication June 15, 2004. Efficacy was based on the posttreatment level of occlusion. Otologic signs and symptoms were also assessed.
See the "Methods" section for a description of Cerumenex, Murine, and placebo products. Signed written informed consent was obtained from all subjects in advance of any study procedures. All clinical assessments were performed by a qualified specialist. Main Outcome Measure. Currently marketed ceruminolytic products primarily act by softening earwax to facilitate its removal with irrigation, rather than by dissolution. Standardized data forms were used to collect demographic information, medical history, current medications, and baseline occlusion status, as well as to document posttreatment outcomes and any complications. 37) and was marginally nonsignificant for Murine compared with placebo (P =. We found the scale, with its qualitative descriptions of occlusion levels, to be effective, particularly in differentiating between complete, mild or moderate, and no occlusion. Of 230 volunteers screened, 74 qualified for enrollment.
A total of 74 subjects ranging in age from 22 to 66 years (mean age, 45 years) were enrolled into the study. Use of the WaterPik for ear irrigation under other conditions is not advised because introducing undue force can be harmful to ear structures. On site limited laboratory services. Sore and Strep Throat. Randomized, Placebo-Controlled Evaluation of Cerumenex and Murine Earwax Removal Products. Our Urgent care clinic in El Cajon California, is a convenient solution to illness, injury, minor emergency or other health care needs, and is an excellent alternative to the emergency room for all your non-life threatening medical conditions requiring immediate care and medical attention. Corporate research clinic. Vitamin B12 Injections. Roland PS, Eaton DA, Gross RD, et al. Descriptive statistics were calculated for (1) the proportion of subjects in each degree of occlusion category at the end of treatment by baseline severity and (2) the proportion of subjects who obtained resolution of their occlusion relative to the subjects who did not obtain resolution.
We can report all tests and progress notes to your primary care physician upon request so they have a history of what was done at East County Urgent Care Center in El Cajon. Participants had baseline occlusion levels of mild (n = 10), moderate (n = 26), or complete (n = 38) impairment of tympanic membrane visualization. Analyses that were performed were done post hoc. In the present study, we compared the effectiveness of 2 marketed ceruminolytic products, Cerumenex Eardrops and Murine Ear Drops, with a saline placebo, BSS Sterile Irrigating Solution, in a controlled clinical setting, in which duration of treatment and method of irrigation were held constant. Our family care physician at East County would be delighted to begin a fruitful medical relationship with you and your family! Earaches and Ear Infections. The test medication was instilled into 1 occluded ear for up to two 15-minute applications. Treatment consisted of up to two 15-minute applications of a ceruminolytic agent or placebo. Training in the use of specialized equipment is required; mechanical removal is potentially damaging to the ear structures if conducted incorrectly. We used a 4-point degree of occlusion scale and found it helpful in differentiating between the severity of occlusions before, during, and after treatment, which allowed us to compare the effectiveness of the test articles.
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